Dodgers vs. Pirates prediction: Why Dodgers are favored to win Wednesday's MLB matchup [9/3/2025]

MLB action continues on Wednesday at 6:40PM ET as the Los Angeles Dodgers lock horns with the Pittsburgh Pirates at PNC Park.

Braxton Ashcraft (4-2, 2.58 ERA) will start on the mound for the Pirates, while the Dodgers have opted for Emmet Sheehan (5-2, 3.56 ERA).

Based on updated simulations, Dimers' proven MLB model predicts the Dodgers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Dodgers-Pirates game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Dodgers' chance of winning at 59%, with the Pirates at 41%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Dodgers vs. Pirates predictions page.

Pirates vs. Dodgers prediction: Who will win, cover the run line?

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's MLB matchup between the Dodgers and Pirates 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Dodgers a 59% chance of beating the Pirates.

According to our model, the Pirates (+1.5) have a 55% chance of covering the run line, while the 8.5-run over/under has a 51% chance of staying under.

Dodgers vs. Pirates odds [9/3/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Dodgers	Pirates
Run Line	-1.5 (-101)	+1.5 (-115)
Moneyline	-165	+144
Total	o8.5 (+102)	u8.5 (-119)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Dodgers vs. Pirates picks and best bets

Our model's strongest edge in today's Dodgers vs. Pirates matchup is on the over/under.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Dodgers vs. Pirates game-day updates and essential details

Wednesday's MLB game between the Pirates and Dodgers at PNC Park is scheduled to start at 6:40PM ET.

• Who: Los Angeles Dodgers vs. Pittsburgh Pirates
• Date: Wednesday, September 3, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's full preview of Wednesday's Dodgers vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Dodgers vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Dodgers, with a 59% win probability, will likely beat the Pirates on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Dodgers vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most accurate probabilities for the World Series, American League, National League and each division.