Dodgers vs. Pirates prediction: Why Dodgers are favored to win Thursday's MLB matchup [9/4/2025]

The Pittsburgh Pirates and Los Angeles Dodgers will meet in MLB action at PNC Park on Thursday, starting at 6:40PM ET.

Paul Skenes (9-9, 2.05 ERA) will be the starting pitcher for the Pirates, while the Dodgers have opted for Blake Snell (3-3, 2.41 ERA).

Based on updated simulations, Dimers' advanced MLB model projects the Dodgers as the most likely winner of today's game.

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Dodgers vs. Pirates predictions page.

Pirates vs. Dodgers prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the outcome of Thursday's MLB game between the Dodgers and Pirates 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Dodgers a 51% chance of beating the Pirates.

According to our model, the Pirates (+1.5) have a 63% chance of covering the run line, while the 7-run over/under has a 51% chance of going over.

Dodgers vs. Pirates odds [9/4/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Dodgers	Pirates
Run Line	-1.5 (+155)	+1.5 (-181)
Moneyline	-115	-102
Total	o7 (+100)	u7 (-117)

All odds are correct at the time of publication and are subject to change.

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Dodgers vs. Pirates picks and best bets

Our model's strongest edge in today's Dodgers vs. Pirates matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Dodgers vs. Pirates game-day updates and essential details

Thursday's MLB matchup between the Pirates and Dodgers at PNC Park is scheduled to start at 6:40PM ET.

• Who: Los Angeles Dodgers vs. Pittsburgh Pirates
• Date: Thursday, September 4, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's in-depth preview of Thursday's Dodgers vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Dodgers vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Dodgers, with a 51% win probability, will likely beat the Pirates on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Dodgers vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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