Dodgers vs. Rockies prediction: Dodgers favored to win Thursday's MLB matchup [8/21/2025]

The Colorado Rockies will square off with the favored Los Angeles Dodgers in MLB action at Coors Field on Thursday, starting at 3:10PM ET.

The Rockies will have Chase Dollander (2-9, 6.43 ERA) as their starting pitcher, pitting him against Clayton Kershaw (7-2, 3.01 ERA) for the Dodgers.

Based on updated simulations, Dimers' advanced MLB model predicts the Dodgers as the most likely winner of today's game.

For a closer look at Thursday's matchup, including best bets and picks, visit our interactive Dodgers vs. Rockies predictions page.

Rockies vs. Dodgers prediction: Who will win, cover the run line?

Using powerful machine learning and statistical analysis, we have simulated the result of Thursday's MLB matchup between the Dodgers and Rockies 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Dodgers a 61% chance of defeating the Rockies.

According to our model, the Dodgers (-1.5) have a 52% chance of covering the run line, while the 12-run over/under has a 55% chance of staying under.

Dodgers vs. Rockies odds [8/21/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Dodgers	Rockies
Run Line	-1.5 (-152)	+1.5 (+137)
Moneyline	-210	+185
Total	o12 (-105)	u12 (-115)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Dodgers vs. Rockies picks and best bets

Our model's strongest edge in today's Dodgers vs. Rockies matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Dodgers vs. Rockies game-day updates and essential details

Thursday's MLB action between the Rockies and Dodgers at Coors Field is scheduled to commence at 3:10PM ET.

• Who: Los Angeles Dodgers vs. Colorado Rockies
• Date: Thursday, August 21, 2025
• Time: 3:10PM ET/12:10PM PT
• Venue: Coors Field

Dimers.com's comprehensive preview of Thursday's Dodgers vs. Rockies matchup includes our prediction, picks and the latest betting odds.

Before making any Dodgers vs. Rockies picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Dodgers, with a 61% win probability, will likely beat the Rockies on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Dodgers vs. Rockies insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest probabilities for the World Series, American League, National League and each division.