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Chargers vs. Raiders prediction: Chargers favored to win MNF Week 2, 2025

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Written by Ryan Leaver

Get Los Angeles Chargers vs Las Vegas Raiders predictions for NFL Monday.

Los Angeles Chargers-Las Vegas Raiders Predictions and Game Preview.
Los Angeles Chargers vs. Las Vegas Raiders NFL prediction for Monday, September 15, 2025.

The Las Vegas Raiders will face the Los Angeles Chargers in NFL Week 2 action at Allegiant Stadium on Monday, beginning at 10:00PM ET.

Based on updated simulations, Dimers' advanced NFL model predicts the Chargers as the most likely winner of today's game.

This gameday Chargers vs. Raiders betting preview builds on my Chargers vs. Raiders prediction that was published earlier in the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Chargers vs. Raiders predictions page.

Chargers vs. Raiders Predictions

Since our Chargers-Raiders predictions earlier in the week, we have simulated the outcome of Monday's NFL game between the Chargers and Raiders 10,000 times as part of our NFL predictions coverage.

Our independent predictive model currently gives the Chargers a 63% chance of beating the Raiders in Week 2 of the NFL season. Our predicted final score has the Chargers winning 24-21.

According to our model, the bookmakers have got it right, and the Chargers and Raiders each have a 50% chance of covering the spread, while the over/under total of 46.5 points has a 53% chance of staying under.

 

Chargers vs. Raiders odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Chargers Raiders
Spread -3.5 (-102) +3.5 (-115)
Moneyline -176 +164
Total o46.5 (-110) u46.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Chargers vs. Raiders picks and best bets

Our model's biggest edge in today's Chargers vs. Raiders matchup is on the spread.

Our expert predictions, matched against the latest odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Chargers vs. Raiders TD scorers

Who will score an anytime touchdown in Chargers vs. Raiders?

According to our model, Las Vegas' Ashton Jeanty is most likely to score the first touchdown in Chargers vs. Raiders.

Our projections give Jeanty a 14.5% chance of scoring the first TD at Allegiant Stadium, while the Raiders running back is a 50.7% chance of scoring an anytime touchdown.

First touchdown scorer predictions

Los Angeles Chargers

Player First TD Probability
Omarion Hampton (RB) 13.0%
Ladd McConkey (WR) 8.8%
Keenan Allen (WR) 6.6%

Las Vegas Raiders

Player First TD Probability
Ashton Jeanty (RB) 14.5%
Jakobi Meyers (WR) 7.4%
Brock Bowers (TE) 7.1%

Anytime touchdown scorer predictions

Los Angeles Chargers

Player Anytime TD Probability
Omarion Hampton (RB) 45.7%
Ladd McConkey (WR) 33.9%
Keenan Allen (WR) 26.7%

Las Vegas Raiders

Player Anytime TD Probability
Ashton Jeanty (RB) 50.7%
Jakobi Meyers (WR) 30.4%
Brock Bowers (TE) 29.1%

Chargers vs Raiders player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Chargers and Raiders. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Chargers-Raiders page now to access every player prop projection.

Chargers vs. Raiders quarterbacks

Of the starting quarterbacks, the Chargers' Justin Herbert is projected to throw for more yards than the Raiders' Geno Smith.

Chargers rushing

Omarion Hampton, Najee Harris and Justin Herbert are projected to be the leading rushers for the Chargers.

Player Position
Omarion Hampton RB
Najee Harris RB
Justin Herbert QB

Raiders rushing

Ashton Jeanty, Geno Smith and Zamir White are expected to lead the Raiders in rushing yards.

Player Position
Ashton Jeanty RB
Geno Smith QB
Zamir White RB

Chargers receiving

Ladd McConkey, Keenan Allen, Quentin Johnston, Will Dissly and Tyler Conklin are projected to top the receiving yards for the Chargers.

Player Position
Ladd McConkey WR
Keenan Allen WR
Quentin Johnston WR
Will Dissly TE
Tyler Conklin TE

Raiders receiving

Jakobi Meyers, Brock Bowers, Tre Tucker, Dont'e Thornton and Michael Mayer are projected to lead the Raiders in receiving yards.

Player Position
Jakobi Meyers WR
Brock Bowers TE
Tre Tucker WR
Dont'e Thornton WR
Michael Mayer TE

Chargers vs. Raiders game-day updates and essential details

The NFL Week 2 action between the Raiders and Chargers at Allegiant Stadium is scheduled to begin at 10:00PM ET.

Dimers' in-depth preview of Monday's Chargers vs. Raiders matchup includes our prediction, picks and the latest betting odds.

Before making any Chargers vs. Raiders picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Chargers, with a 63% win probability, will likely beat the Raiders in Week 2 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Chargers vs. Raiders insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on NFL

Stay up-to-date with the latest NFL news and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the most up-to-date predictions for the Super Bowl, AFC, NFC and each division.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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