Angels vs. Cardinals Prediction: St. Louis Predicted to Win Wednesday's MLB Matchup [4/2/2025]

The St. Louis Cardinals will face the Los Angeles Angels in MLB action at Busch Stadium on Wednesday, beginning at 1:15PM ET.

Sonny Gray (1-0, 3.60 ERA) will get the ball for the Cardinals, while the Angels have opted for Yusei Kikuchi (0-1, 4.50 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's LA Angels-St. Louis game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Cardinals' chance of winning at 57%, with the Angels at 43%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Angels vs. Cardinals predictions page.

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Angels vs. Angels Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the outcome of Wednesday's MLB matchup between the Angels and Cardinals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Cardinals a 57% chance of defeating the Angels.

According to our model, the Angels (+1.5) have a 63% chance of covering the run line, while the over/under total of 8.5 runs has a 54% chance of staying under.

Angels vs. Cardinals Odds [4/2/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Angels	Cardinals
Run Line	+1.5 (-166)	-1.5 (+154)
Moneyline	+130	-142
Total	o8.5 (-112)	u8.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Angels vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Angels vs. Cardinals matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Angels vs. Cardinals Game-Day Updates and Essential Details

Wednesday's MLB action between the Cardinals and Angels at Busch Stadium is scheduled to start at 1:15PM ET.

• Who: Los Angeles Angels vs. St. Louis Cardinals
• Date: Wednesday, April 2, 2025
• Time: 1:15PM ET/10:15AM PT
• Venue: Busch Stadium

Dimers.com's in-depth preview of Wednesday's Angels vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any LA Angels vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cardinals, with a 57% win probability, will likely beat the Angels on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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