Angels vs. Mariners Prediction: Seattle Predicted to Win Wednesday's MLB Matchup [4/30/2025]

The Seattle Mariners will take on the Los Angeles Angels in MLB action at T-Mobile Park on Wednesday, starting at 4:10PM ET.

Emerson Hancock (1-1, 7.71 ERA) will start on the mound for the Mariners, pitting him against Tyler Anderson (2-0, 2.60 ERA) for the Angels.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Mariners as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's LA Angels-Seattle game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Mariners' chance of winning at 53%, with the Angels at 47%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Angels vs. Mariners predictions page.

Mariners vs. Angels Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Angels and Mariners 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Mariners a 53% chance of defeating the Angels.

According to our model, the Angels (+1.5) have a 65% chance of covering the run line, while the over/under total of 8.5 runs has a 52% chance of staying under.

Angels vs. Mariners Odds [4/30/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Angels	Mariners
Run Line	+1.5 (-165)	-1.5 (+150)
Moneyline	+120	-138
Total	o8.5 (+100)	u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Angels vs. Mariners Picks and Best Bets

Our model's biggest edge in today's Angels vs. Mariners matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Angels vs. Mariners Game-Day Updates and Essential Details

Wednesday's MLB game between the Mariners and Angels at T-Mobile Park is scheduled to begin at 4:10PM ET.

• Who: Los Angeles Angels vs. Seattle Mariners
• Date: Wednesday, April 30, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: T-Mobile Park

Dimers.com's in-depth preview of Wednesday's Angels vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any LA Angels vs. Seattle picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Mariners, with a 53% win probability, will likely beat the Angels on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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