Angels vs. Mariners prediction: Seattle favored to win Thursday's MLB matchup [9/11/2025]

The Seattle Mariners will face the Los Angeles Angels in MLB action at T-Mobile Park on Thursday, commencing at 9:40PM ET.

The Mariners will start Bryce Miller (4-5, 5.53 ERA), while the Angels will counter with José Soriano (10-10, 4.07 ERA).

Based on updated simulation results, Dimers' proven MLB model projects the Mariners as the most likely winner of today's game.

For further insights into Thursday's matchup, including best bets and picks, visit our interactive Angels vs. Mariners predictions page.

Mariners vs. Angels prediction: Who will win, cover the run line?

Using trusted machine learning and data analysis, we have simulated the outcome of Thursday's MLB matchup between the Angels and Mariners 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Mariners a 60% chance of beating the Angels.

According to our model, the Angels (+1.5) have a 60% chance of covering the run line, while the 7.5-run over/under has a 55% chance of going over.

Angels vs. Mariners odds [9/11/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Angels	Mariners
Run Line	+1.5 (-154)	-1.5 (+130)
Moneyline	+140	-164
Total	o7.5 (-115)	u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Angels vs. Mariners picks and best bets

Our model's strongest edge in today's Angels vs. Mariners matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Angels vs. Mariners game-day updates and essential details

Thursday's MLB game between the Mariners and Angels at T-Mobile Park is scheduled to start at 9:40PM ET.

• Who: Los Angeles Angels vs. Seattle Mariners
• Date: Thursday, September 11, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: T-Mobile Park

Dimers' in-depth preview of Thursday's Angels vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any Angels vs. Mariners picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Mariners, with a 60% win probability, will likely beat the Angels on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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