Angels vs. Padres Prediction: San Diego Predicted to Win Tuesday's MLB Matchup [5/13/2025]

The San Diego Padres will square off with the Los Angeles Angels in MLB action at PETCO Park on Tuesday, starting at 9:40PM ET.

Dylan Cease (1-2, 4.91 ERA) will start on the mound for the Padres, while the Angels have opted for José Soriano (2-4, 4.00 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Padres as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's LA Angels-San Diego game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Padres with a win probability of 67%, compared to 33% for the Angels."

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Angels vs. Padres predictions page.

Padres vs. Angels Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Tuesday's MLB matchup between the Angels and Padres 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Padres a 67% chance of beating the Angels.

According to our model, the Angels (+1.5) have a 53% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of staying under.

Angels vs. Padres Odds [5/13/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Angels	Padres
Run Line	+1.5 (-118)	-1.5 (+100)
Moneyline	+184	-218
Total	o7.5 (-102)	u7.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Angels vs. Padres Picks and Best Bets

Our model's strongest edge in today's Angels vs. Padres matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Angels vs. Padres Game-Day Updates and Essential Details

Tuesday's MLB game between the Padres and Angels at PETCO Park is scheduled to start at 9:40PM ET.

• Who: Los Angeles Angels vs. San Diego Padres
• Date: Tuesday, May 13, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: PETCO Park

Dimers.com's full preview of Tuesday's Angels vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any LA Angels vs. San Diego picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Padres, with a 67% win probability, will likely beat the Angels on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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