Angels vs. Brewers prediction: Cy Young candidate Freddy Peralta takes on Angels tonight [9/16/2025]

The Milwaukee Brewers and Los Angeles Angels are scheduled to meet in MLB action at American Family Field on Tuesday, starting at 7:40PM ET.

Cy Young hopeful Freddy Peralta (16-6, 2.70 ERA) will start for the Brewers, pitting him against Caden Dana (0-1, 6.32 ERA) for the Angels.

Based on the latest simulations, Dimers' proven MLB model predicts the Brewers as the most likely winner of today's game.

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Angels vs. Brewers predictions page.

Brewers vs. Angels prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the result of Tuesday's MLB matchup between the Angels and Brewers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Brewers a 68% chance of beating the Angels.

According to our model, the bookmakers have got it right, and the Angels and Brewers each have a 50% chance of covering the run line, while the 8.5-run over/under has a 51% chance of going over.

Angels vs. Brewers odds [9/16/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Angels	Brewers
Run Line	+1.5 (+108)	-1.5 (-125)
Moneyline	+222	-270
Total	o8.5 (-105)	u8.5 (-109)

All odds are correct at the time of publication and are subject to change.

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Angels vs. Brewers picks and best bets

Our model's strongest edge in today's Angels vs. Brewers matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Angels vs. Brewers game-day updates and essential details

Tuesday's MLB action between the Brewers and Angels at American Family Field is scheduled to start at 7:40PM ET.

• Who: Los Angeles Angels vs. Milwaukee Brewers
• Date: Tuesday, September 16, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: American Family Field

Dimers' full preview of Tuesday's Angels vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Angels vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Brewers, with a 68% win probability, will likely beat the Angels on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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