Angels vs. Brewers prediction: Why Milwaukee is favored to win Thursday's MLB matchup [9/18/2025]

The Milwaukee Brewers and Los Angeles Angels are scheduled to meet in MLB action at American Family Field on Thursday, starting at 7:40PM ET.

Quinn Priester (13-2, 3.25 ERA) will get the ball for the Brewers, up against Yusei Kikuchi (6-11, 4.08 ERA) for the Angels.

Based on updated simulation results, Dimers' advanced MLB model predicts the Brewers as the most likely winner of today's game.

For a closer look at Thursday's matchup, including best bets and picks, visit our interactive Angels vs. Brewers predictions page.

Brewers vs. Angels prediction: Who will win, cover the run line?

Using innovative machine learning and data, we have simulated the outcome of Thursday's MLB matchup between the Angels and Brewers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Brewers a 66% chance of beating the Angels.

According to our model, the Angels (+1.5) have a 52% chance of covering the run line, while the over/under total of 8 runs has a 52% chance of going over.

Angels vs. Brewers odds [9/18/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Angels	Brewers
Run Line	+1.5 (+105)	-1.5 (-118)
Moneyline	+207	-250
Total	o8 (-110)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

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Angels vs. Brewers picks and best bets

Our model's strongest edge in today's Angels vs. Brewers matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Angels vs. Brewers game-day updates and essential details

Thursday's MLB matchup between the Brewers and Angels at American Family Field is scheduled to start at 7:40PM ET.

• Who: Los Angeles Angels vs. Milwaukee Brewers
• Date: Thursday, September 18, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: American Family Field

Dimers' comprehensive preview of Thursday's Angels vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Angels vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Brewers, with a 66% win probability, will likely beat the Angels on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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