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Angels vs. Astros prediction: Houston favored to win Labor Day MLB matchup [9/1/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Los Angeles Angels vs Houston Astros predictions for MLB Labor Day.
The Houston Astros and Los Angeles Angels are scheduled to meet in MLB action at Daikin Park on Monday, starting at 2:10PM ET.
The Astros will start Luis Garcia (0-0, 0.00 ERA), pitting him against Yusei Kikuchi (6-9, 3.68 ERA) for the Angels.
Based on the latest simulations, Dimers' proven MLB model projects the Astros as the most likely winner of today's game.
For a closer look at Monday's matchup, including best bets and picks, visit our interactive Angels vs. Astros predictions page.
Astros vs. Angels prediction: Who will win, cover the run line?
Using powerful machine learning and data analysis, we have simulated the outcome of Monday's MLB matchup between the Angels and Astros 10,000 times as part of our MLB predictions coverage.
Our independent predictive model currently gives the Astros a 59% chance of defeating the Angels.
According to our model, the Angels (+1.5) have a 60% chance of covering the run line, while the 8-run over/under has a 53% chance of going over.
Angels vs. Astros odds [9/1/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Angels | Astros |
|---|---|---|
| Run Line | +1.5 (-152) | -1.5 (+135) |
| Moneyline | +140 | -162 |
| Total | o8 (-120) | u8 (-101) |
All odds are correct at the time of publication and are subject to change.
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Angels vs. Astros picks and best bets
Our model's strongest edge in today's Angels vs. Astros matchup is on the over/under.
Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's free MLB picks
Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.
Angels vs. Astros game-day updates and essential details
Monday's MLB matchup between the Astros and Angels at Daikin Park is scheduled to commence at 2:10PM ET.
- Who: Los Angeles Angels vs. Houston Astros
- Date: Monday, September 1, 2025
- Time: 2:10PM ET/11:10AM PT
- Venue: Daikin Park
Dimers.com's in-depth preview of Monday's Angels vs. Astros matchup includes our prediction, picks and the latest betting odds.
Before making any Angels vs. Astros picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Astros, with a 59% win probability, will likely beat the Angels on Monday.
AI and automation have enhanced this article to quickly deliver accurate Angels vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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