Angels vs. Astros prediction: Houston favored to win Friday's MLB matchup [8/29/2025]

The Houston Astros will take on the Los Angeles Angels in MLB action at Daikin Park on Friday, beginning at 8:10PM ET.

The Astros will send Cristian Javier (1-1, 5.40 ERA) to the mound, up against Tyler Anderson (2-8, 4.73 ERA) for the Angels.

Based on updated simulations, Dimers' advanced MLB model projects the Astros as the most likely winner of today's game.

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Angels vs. Astros predictions page.

Astros vs. Angels prediction: Who will win, cover the run line?

Using innovative machine learning and data, we have simulated the outcome of Friday's MLB matchup between the Angels and Astros 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Astros a 60% chance of beating the Angels.

According to our model, the Angels (+1.5) have a 58% chance of covering the run line, while the 9-run over/under has a 51% chance of going over.

Angels vs. Astros odds [8/29/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Angels	Astros
Run Line	+1.5 (-150)	-1.5 (+128)
Moneyline	+140	-162
Total	o9 (-115)	u9 (-105)

All odds are correct at the time of publication and are subject to change.

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Angels vs. Astros picks and best bets

Our model's biggest edge in today's Angels vs. Astros matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Angels vs. Astros game-day updates and essential details

Friday's MLB game between the Astros and Angels at Daikin Park is scheduled to begin at 8:10PM ET.

• Who: Los Angeles Angels vs. Houston Astros
• Date: Friday, August 29, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's in-depth preview of Friday's Angels vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Angels vs. Astros picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Astros, with a 60% win probability, will likely beat the Angels on Friday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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