Lorenzo Musetti vs. Giovanni Mpetshi Perricard prediction, odds, picks for US Open 2025

Lorenzo Musetti will take on Giovanni Mpetshi Perricard in the first round of the US Open Men's Singles 2025 on Tuesday.

Based on updated simulation results, Dimers' proven tennis model projects Lorenzo Musetti as the most likely winner of the match.

For expanded analysis of Tuesday's match, including best bets and picks, visit our interactive Musetti vs. Mpetshi Perricard predictions page.

Musetti vs. Mpetshi Perricard prediction: Who will win and advance to the Second Round?

Using powerful machine learning and data, we have simulated the outcome of Tuesday's Musetti-Mpetshi Perricard men's singles match 10,000 times as part of our tennis predictions coverage.

Our independent predictive model currently gives Musetti a 69% chance of defeating Mpetshi Perricard in the US Open 2025.

Additionally, Musetti has a 65% chance of winning the first set. The simulations also show Musetti (-3.5) has a 53% chance of covering the games spread, while the under 42.5 games has a 69% chance of hitting, according to our model.

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Lorenzo Musetti vs. Giovanni Mpetshi Perricard odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Musetti	Mpetshi Perricard
Moneyline	-240	+200
First Set	-189	+150
Game Spread	+3.5 (-110)	-3.5 (-120)
Total Games	o42.5 (-110)	u42.5 (-125)

All odds are correct at the time of publication and are subject to change.

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Musetti vs. Mpetshi Perricard picks and best bets

Our model's strongest edge in today's Musetti vs. Mpetshi Perricard match is on the first set.

Our expert predictions, matched against the latest odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Musetti vs. Mpetshi Perricard updates and essential details

The US Open 2025 match between Lorenzo Musetti and Giovanni Mpetshi Perricard is scheduled to start on Tuesday at 11:00AM ET.

• Who: Lorenzo Musetti vs. Giovanni Mpetshi Perricard
• Date: Tuesday, August 26, 2025
• Approx. Time: 11:00AM ET/8:00AM PT
• Tournament: US Open Men's Singles 2025
• Round: First round

All dates and times in this article are United States Eastern Time unless otherwise noted.

Dimers.com's in-depth preview of Tuesday's Musetti vs. Mpetshi Perricard match includes our prediction, picks and the latest betting odds.

Before making any Lorenzo Musetti vs. Giovanni Mpetshi Perricard picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Lorenzo Musetti, with a 69% win probability, will likely beat Giovanni Mpetshi Perricard at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Musetti vs. Mpetshi Perricard insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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