Lorenzo Musetti vs. David Goffin prediction, odds, picks for US Open 2025

Lorenzo Musetti and David Goffin will lock horns in the second round of the US Open 2025 on Thursday.

Based on updated simulation results, Dimers' proven tennis model predicts Lorenzo Musetti as the most likely winner of the match.

For a closer look at Thursday's match, including best bets and picks, visit our interactive Musetti vs. Goffin predictions page.

Musetti vs. Goffin prediction: Who will win and advance to the Round of 32?

Using innovative machine learning and statistical analysis, we have simulated the result of Thursday's Musetti-Goffin men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Musetti an 85% chance of beating Goffin in the US Open 2025.

Additionally, Musetti has a 77% chance of winning the first set, while the over 32.5 games has a 52% chance of hitting, according to our model.

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Lorenzo Musetti vs. David Goffin odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Musetti	Goffin
Moneyline	-714	+530
First Set	-333	+250
Total Games	o32.5 (-110)	u32.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Musetti vs. Goffin picks and best bets

Our model's biggest edge in today's Musetti vs. Goffin match is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Musetti vs. Goffin updates and essential details

The US Open 2025 match between Lorenzo Musetti and David Goffin is scheduled to start on Thursday at 11:00AM ET.

• Who: Lorenzo Musetti vs. David Goffin
• Date: Thursday, August 28, 2025
• Approx. Time: 11:00AM ET/8:00AM PT
• Tournament: US Open Men's Singles 2025
• Round: Second round

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Dimers.com's comprehensive preview of Thursday's Musetti vs. Goffin match includes our prediction, picks and the latest betting odds.

Before making any Lorenzo Musetti vs. David Goffin picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Lorenzo Musetti, with an 85% win probability, will likely beat David Goffin at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Musetti vs. Goffin insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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