Liberty vs. Jacksonville State prediction: Liberty favored to win in college football Week 2, 2025

Jacksonville State will face the favored Liberty in Week 2 college football action at AmFirst Stadium on Saturday, starting at 12:00PM ET.

Based on updated simulation results, Dimers' advanced college football model predicts Liberty as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Liberty vs. Jacksonville State predictions page.

Liberty vs. Jacksonville State prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the outcome of Liberty vs. Jacksonville State 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Liberty a 62% chance of beating Jacksonville State. Our predicted final score has Liberty winning 26-22.

According to our model, Jacksonville State (+6.5) has a 54% chance of covering the spread, while the over/under total of 50.5 points has an equal 50-50 chance of hitting.

Liberty vs. Jacksonville State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Liberty	Jacksonville State
Spread	-6.5 (-105)	+6.5 (-115)
Moneyline	-220	+190
Total	o50.5 (-110)	u50.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Liberty vs. Jacksonville State picks and best bets

Our model's strongest edge in today's Liberty vs. Jacksonville State matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Liberty vs. Jacksonville State game-day updates and essential details

Saturday's college football matchup between Jacksonville State and Liberty at AmFirst Stadium is scheduled to begin at 12:00PM ET.

• Who: Liberty vs. Jacksonville State
• Date: Saturday, September 6, 2025
• Time: 12:00PM ET/9:00AM PT
• Venue: AmFirst Stadium

Dimers.com's comprehensive preview of Saturday's Liberty vs. Jacksonville State matchup includes our prediction, picks and the latest betting odds.

Before making any Liberty vs. Jacksonville State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Liberty, with a 62% win probability, will likely beat Jacksonville State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Liberty vs. Jacksonville State insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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