Las Vegas Raiders vs. New England Patriots early prediction: Expert picks for NFL Week 1, 2025

The Las Vegas Raiders and New England Patriots will meet in Week 1 of the NFL season at Gillette Stadium on Sunday, September 7, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Patriots as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Raiders vs. Patriots predictions page.

Las Vegas vs. New England early predictions

Leveraging trusted machine learning and analysis, we have simulated the Raiders vs. Patriots game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Raiders 41%, Patriots 59%
• Predicted final score: Raiders 20-22 Patriots
• Spread: Raiders (+2.5) 50%, Patriots (-2.5) 50%
• Total points (43.5): Over 46%, Under 54%

As of August 31, 2025, these Raiders-Patriots numbers and predictions reflect the latest data and insights available.

Raiders vs. Patriots Week 1 details

The NFL Week 1 game between the Patriots and Raiders at Gillette Stadium is scheduled for September 7, 2025.

• Who: Las Vegas Raiders vs. New England Patriots
• Date: Sunday, September 7, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Gillette Stadium

Raiders vs. Patriots opening odds

We've researched the best betting odds across America for this Week 1 game, which are listed here:

• Spread: Raiders +2.5 (-104), Patriots -2.5 (-115)
• Moneyline: Raiders +130, Patriots -145
• Total: Over/Under 43.5 (-105/-115)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Patriots, with a 59% win probability, will likely beat the Raiders in Week 1 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Raiders vs. Patriots game, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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