Karen Khachanov vs. Alexander Zverev Prediction, Odds, Picks for ATP Cincinnati Open 2025

Karen Khachanov and Alexander Zverev will lock horns in the round of 16 of the ATP Cincinnati Open event on Wednesday.

Based on the latest simulation results, Dimers' advanced tennis model (see Dimers Pro for full access) projects Alexander Zverev as the most likely winner of the match. "We have simulated the outcome of Wednesday's Khachanov-Zverev match 10,000 times," said Dimers data analyst Greg Butyn.

"With the latest updates and numerous other variables, we estimate Alexander Zverev's chance of winning at 61%, with Karen Khachanov at 39%."

For a closer look at Wednesday's match, including best bets and picks, visit our interactive Khachanov vs. Zverev predictions page.

Khachanov vs. Zverev Prediction: Who Will Win and Advance to the Quarterfinals?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's Khachanov-Zverev men's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model currently gives Zverev a 61% chance of defeating Khachanov at the ATP Cincinnati Open tournament.

Additionally, Zverev has a 58% chance of winning the first set, according to our model.

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Karen Khachanov vs. Alexander Zverev Odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Khachanov	Zverev
Moneyline	+175	-227
First Set	+137	-175

All odds are correct at the time of publication and are subject to change.

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Khachanov vs. Zverev Picks and Best Bets

Our model's biggest edge in today's Khachanov vs. Zverev match is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Khachanov vs. Zverev Updates and Essential Details

The ATP Cincinnati Open match between Karen Khachanov and Alexander Zverev is scheduled to start on Wednesday at 9:10PM ET.

• Who: Karen Khachanov vs. Alexander Zverev
• Date: Wednesday, August 13, 2025
• Approx. Time: 9:10PM ET/6:10PM PT
• Tournament: ATP Cincinnati, USA Men's Singles 2025
• Round: Round of 16

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's comprehensive preview of Wednesday's Khachanov vs. Zverev match includes our prediction, picks and the latest betting odds.

Before making any Karen Khachanov vs. Alexander Zverev picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Alexander Zverev, with a 61% win probability, will likely beat Karen Khachanov at the ATP Cincinnati Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Khachanov vs. Zverev insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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