Kansas vs. Missouri prediction: Why Missouri is favored to win in college football Week 2, 2025

Missouri will face Kansas in Week 2 college football action at Memorial Stadium/Faurot Field on Saturday, starting at 3:30PM ET.

Based on updated simulations, Dimers' proven college football model predicts Missouri as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Kansas vs. Missouri predictions page.

Kansas vs. Missouri prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the result of Kansas vs. Missouri 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Missouri a 62% chance of beating Kansas. Our predicted final score has Missouri winning 27-23.

According to our model, Kansas (+7.5) has a 56% chance of covering the spread, while the over/under total of 50.5 points has a 54% chance of staying under.

Kansas vs. Missouri odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Kansas	Missouri
Spread	+7.5 (-104)	-7.5 (-128)
Moneyline	+250	-200
Total	o50.5 (-110)	u50.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Kansas vs. Missouri picks and best bets

Our model's biggest edge in today's Kansas vs. Missouri matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Kansas vs. Missouri game-day updates and essential details

Saturday's college football game between Missouri and Kansas at Memorial Stadium/Faurot Field is scheduled to commence at 3:30PM ET.

• Who: Kansas vs. Missouri
• Date: Saturday, September 6, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Memorial Stadium/Faurot Field

Dimers.com's in-depth preview of Saturday's Kansas vs. Missouri matchup includes our prediction, picks and the latest betting odds.

Before making any Kansas vs. Missouri picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Missouri, with a 62% win probability, will likely beat Kansas on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Kansas vs. Missouri insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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