Royals vs. Twins Prediction: Minnesota Predicted to Win Friday's MLB Matchup [5/23/2025]

The Minnesota Twins will take on the Kansas City Royals in MLB action at Target Field on Friday, beginning at 8:10PM ET.

Pablo López (4-2, 2.40 ERA) will start on the mound for the Twins, up against Noah Cameron (1-1, 0.71 ERA) for the Royals.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Twins as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Kansas City-Minnesota game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Twins' chance of winning is 62%, while the Royals' is 38%."

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Royals vs. Twins predictions page.

Twins vs. Royals Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the outcome of Friday's MLB matchup between the Royals and Twins 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Twins a 62% chance of defeating the Royals.

According to our model, the Royals (+1.5) have a 57% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of going over.

Royals vs. Twins Odds [5/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Royals	Twins
Run Line	+1.5 (-135)	-1.5 (+118)
Moneyline	+160	-190
Total	o7.5 (-115)	u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Royals vs. Twins Picks and Best Bets

Our model's strongest edge in today's Royals vs. Twins matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Royals vs. Twins Game-Day Updates and Essential Details

Friday's MLB action between the Twins and Royals at Target Field is scheduled to begin at 8:10PM ET.

• Who: Kansas City Royals vs. Minnesota Twins
• Date: Friday, May 23, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Target Field

Dimers.com's in-depth preview of Friday's Royals vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any Kansas City vs. Minnesota picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Twins, with a 62% win probability, will likely beat the Royals on Friday.

AI and automation have enhanced this article to quickly deliver accurate Royals vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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