Royals vs. Astros Prediction: Houston Predicted to Win Wednesday's MLB Matchup [5/14/2025]

The Houston Astros and Kansas City Royals are scheduled to meet in MLB action at Daikin Park on Wednesday, starting at 8:10PM ET.

The Astros will have Colton Gordon (0-0, 0.00 ERA) as their starting pitcher, up against Michael Lorenzen (3-3, 3.57 ERA) for the Royals.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Kansas City-Houston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Astros' chance of winning at 53%, with the Royals at 47%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Royals vs. Astros predictions page.

Astros vs. Royals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Wednesday's MLB game between the Royals and Astros 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Astros a 53% chance of defeating the Royals.

According to our model, the Royals (+1.5) have a 64% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

Royals vs. Astros Odds [5/14/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Royals	Astros
Run Line	+1.5 (-185)	-1.5 (+164)
Moneyline	+108	-122
Total	o8.5 (-112)	u8.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Royals vs. Astros Picks and Best Bets

Our model's strongest edge in today's Royals vs. Astros matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Royals vs. Astros Game-Day Updates and Essential Details

Wednesday's MLB action between the Astros and Royals at Daikin Park is scheduled to start at 8:10PM ET.

• Who: Kansas City Royals vs. Houston Astros
• Date: Wednesday, May 14, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Wednesday's Royals vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Kansas City vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Astros, with a 53% win probability, will likely beat the Royals on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Royals vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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