Royals vs. Astros Prediction: Houston Predicted to Win Monday's MLB Matchup [5/12/2025]

MLB action continues on Monday at 8:10PM ET as the Kansas City Royals square off with the Houston Astros at Daikin Park.

Ryan Gusto (3-1, 2.93 ERA) will get the ball for the Astros, while the Royals have opted for Michael Wacha (2-4, 2.98 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Kansas City-Houston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Astros are likely to win, with a probability of 53%, compared to the Royals' 47%."

For further insights into Monday's matchup, including best bets and picks, visit our interactive Royals vs. Astros predictions page.

Astros vs. Royals Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Monday's MLB game between the Royals and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Astros a 53% chance of defeating the Royals.

According to our model, the Royals (+1.5) have a 65% chance of covering the run line, while the over/under total of 8 runs has a 51% chance of going over.

Royals vs. Astros Odds [5/12/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Royals	Astros
Run Line	+1.5 (-192)	-1.5 (+164)
Moneyline	+110	-120
Total	o8 (-112)	u8 (-102)

All odds are correct at the time of publication and are subject to change.

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Royals vs. Astros Picks and Best Bets

Our model's strongest edge in today's Royals vs. Astros matchup is on the total.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Royals vs. Astros Game-Day Updates and Essential Details

Monday's MLB action between the Astros and Royals at Daikin Park is scheduled to commence at 8:10PM ET.

• Who: Kansas City Royals vs. Houston Astros
• Date: Monday, May 12, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's comprehensive preview of Monday's Royals vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Kansas City vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Astros, with a 53% win probability, will likely beat the Royals on Monday.

AI and automation have enhanced this article to quickly deliver accurate Royals vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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