Royals vs. Guardians prediction: Why Kansas City is favored to win Monday's MLB matchup [9/8/2025]

MLB action continues on Monday at 6:40PM ET as the Kansas City Royals square off with the Cleveland Guardians at Progressive Field.

The Guardians will have Slade Cecconi (5-6, 4.78 ERA) as their starting pitcher, while the Royals will counter with Ryan Bergert (2-1, 2.61 ERA).

Based on updated simulations, Dimers' advanced MLB model predicts the Royals as the most likely winner of today's game.

For further insights into Monday's matchup, including best bets and picks, visit our interactive Royals vs. Guardians predictions page.

Guardians vs. Royals prediction: Who will win?

Using powerful machine learning and data, we have simulated the outcome of Monday's MLB game between the Royals and Guardians 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Royals a 51% chance of beating the Guardians.

According to our model, the 7.5-run over/under has a 57% chance of going over.

Royals vs. Guardians odds [9/8/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Royals	Guardians
Moneyline	-104	-110
Total	o7.5 (-108)	u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Royals vs. Guardians picks and best bets

Our model's strongest edge in today's Royals vs. Guardians matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Royals vs. Guardians game-day updates and essential details

Monday's MLB game between the Guardians and Royals at Progressive Field is scheduled to commence at 6:40PM ET.

• Who: Kansas City Royals vs. Cleveland Guardians
• Date: Monday, September 8, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Progressive Field

Dimers' comprehensive preview of Monday's Royals vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Royals vs. Guardians picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Royals, with a 51% win probability, will likely beat the Guardians on Monday.

AI and automation have enhanced this article to quickly deliver accurate Royals vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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