Iowa State vs. Houston Prediction: Houston Predicted to Win College Basketball Matchup [2/22/2025]

Houston will face Iowa State in college basketball action at Fertitta Center on Saturday, commencing at 2:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model (see Dimers Pro for full access) predicts Houston as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Our team has used the latest data to run 10,000 simulations of Saturday's Iowa State-Houston game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that Houston is more likely to win, while Iowa State has a lower chance of victory."

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Iowa State vs. Houston predictions page.

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Iowa State vs. Houston Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data, we have simulated the result of Saturday's NCAA basketball game between Iowa State and Houston 10,000 times as part of our college basketball predictions coverage.

Our famous predictive model currently gives Houston a 91% chance of beating Iowa State. Our predicted final score has Houston winning 72-58.

According to our model, Houston (-12.5) has a 54% chance of covering the spread, while the 130.5-point over/under has a 53% chance of going over.

Iowa State vs. Houston Odds

We have sourced the best College Basketball odds in America for this game, which are listed here:

Bet Type	Iowa State	Houston
Spread	+12.5 (-118)	-12.5 (-104)
Moneyline	+590	-850
Total	o130.5 (-106)	u130.5 (-114)

All odds are correct at the time of publication and are subject to change.

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Iowa State vs. Houston Picks and Best Bets

Our model's strongest edge in today's Iowa State vs. Houston matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Iowa State vs. Houston Game-Day Updates and Essential Details

Saturday's college basketball game between Houston and Iowa State at Fertitta Center is scheduled to begin at 2:00PM ET.

• Who: Iowa State vs. Houston
• Date: Saturday, February 22, 2025
• Time: 2:00PM ET/11:00AM PT
• Venue: Fertitta Center

Dimers.com's comprehensive preview of Saturday's Iowa State vs. Houston matchup includes our prediction, picks and the latest betting odds.

Before making any Iowa State vs. Houston picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

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Conclusion

We predict Houston, with a 91% win probability, will likely beat Iowa State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Iowa State vs. Houston insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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