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Indiana State vs. Southern Illinois Prediction: Southern Illinois Predicted to Win College Basketball Matchup [3/6/2025]
Our expert prediction for Thursday's Indiana State vs Southern Illinois matchup.

Southern Illinois will take on Indiana State, in what is expected to be a close College Basketball game, at Enterprise Center on Thursday, beginning at 1:00PM ET.
Based on updated simulations, Dimers' advanced college basketball model (see Dimers Pro for full access) projects Southern Illinois as the most likely winner of today's game.
Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.
"Using the latest data, our experts simulated Thursday's Indiana State-Southern Illinois game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"Taking into account recent updates and various additional inputs, we forecast Southern Illinois with a win probability of 52% and Indiana State with 48%."
For a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Indiana State vs. Southern Illinois predictions page.
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Indiana State vs. Southern Illinois Prediction: Who Will Win, Cover the Spread?
Using innovative machine learning and data analysis, we have simulated the outcome of Thursday's NCAA basketball game between Indiana State and Southern Illinois 10,000 times as part of our college basketball predictions coverage.
Our independent predictive model gives Southern Illinois a 52% chance of beating Indiana State. Our predicted score is Indiana State 75-75 Southern Illinois.
According to our model, Southern Illinois (+1.5) has a 55% chance of covering the spread, while the over/under total of 153.5 points has a 54% chance of staying under.
While there is no way for a College Basketball game to end in a tie, our prediction of 75-75 is based on each team's average score in the above-mentioned simulations of Indiana State vs. Southern Illinois.
Indiana State vs. Southern Illinois Odds
We have researched the best College Basketball odds in America for this game, which are listed here:
Bet Type | Indiana State | Southern Illinois |
---|---|---|
Spread | -1.5 (-105) | +1.5 (-115) |
Moneyline | -114 | +102 |
Total | o153.5 (-110) | u153.5 (-105) |
All odds are correct at the time of publication and are subject to change.
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Our model's strongest edge in today's Indiana State vs. Southern Illinois matchup is on the spread.
Our expert predictions, matched against the best odds, reveal the best college basketball picks for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
Indiana State vs. Southern Illinois Game-Day Updates and Essential Details
Thursday's college basketball action between Southern Illinois and Indiana State at Enterprise Center is scheduled to begin at 1:00PM ET.
- Who: Indiana State vs. Southern Illinois
- Date: Thursday, March 6, 2025
- Time: 1:00PM ET/10:00AM PT
- Venue: Enterprise Center
Dimers.com's in-depth preview of Thursday's Indiana State vs. Southern Illinois matchup includes our prediction, picks and the latest betting odds.
Before making any Indiana State vs. Southern Illinois picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.
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Conclusion
We predict Southern Illinois, with a 52% win probability, will likely beat Indiana State on Thursday.
AI and automation have enhanced this article to quickly deliver accurate Indiana State vs. Southern Illinois insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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