Pacers vs. Knicks Prediction: New York to Win, Jalen Brunson Projected for Big Game in Game 1 of CF [2025]

The New York Knicks will face the Indiana Pacers in Game 1 of the 2025 NBA Conference Finals at Madison Square Garden on Wednesday, beginning at 8:00PM ET.

Based on the latest simulations and today’s injury updates, Dimers' proven NBA model (see Dimers Pro for full access) predicts the Knicks as the most likely winner of Game 1.

"Our team has simulated the outcome of Wednesday's Indiana-New York game 10,000 times," said Damien Souness from Dimers.

"With the latest updates and numerous other variables, we estimate the Knicks' chance of winning at 66%, with the Pacers at 34%."

This prediction follows the latest NBA Injury Report, which suggests the Knicks lineup will feature stars like Jalen Brunson, Karl-Anthony Towns and Mikal Bridges, while the Pacers will rely on Pascal Siakam, Tyrese Haliburton and Myles Turner.

For further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Pacers vs. Knicks predictions page.

Knicks vs. Pacers Prediction: Who Will Win Game 1?

Using powerful machine learning and data analysis, we have simulated the result of Wednesday's NBA Playoffs game between the Pacers and Knicks 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Knicks a 66% chance of beating the Pacers in Game 1 of the 2025 Conference Finals. Our predicted final score in Game 1 of the 2025 NBA Conference Finals has the Knicks winning 112-108.

According to our model, the Knicks (-4.5) have a 51% chance of covering the spread, while the over/under total of 221.5 points has an equal 50-50 chance of hitting.

Pacers vs. Knicks Game 1 Odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Pacers	Knicks
Spread	+4.5 (-110)	-4.5 (-105)
Moneyline	+160	-186
Total	o221.5 (-108)	u221.5 (-110)

All odds are correct at the time of publication and are subject to change.

Boost your NBA betting by exploring the latest NBA betting promos, sourced from top sportsbooks and DFS operators.

Pacers vs. Knicks Picks and Best Bets for Game 1

Our model's strongest edge in today's Pacers vs. Knicks matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best NBA picks and NBA best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Pacers vs. Knicks Game 1 Player Props

NBA prop bets are an enjoyable way to wager on Wednesday's Indiana vs. New York matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Madison Square Garden.

Pascal Siakam is expected to lead the Pacers in scoring, while Jalen Brunson is projected to be the top scorer for the Knicks.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily NBA betting content, including the best bets featured below.

Pacers vs. Knicks Game 1 Updates and Essential Details

Wednesday's Game 1 between the Knicks and Pacers in the NBA Conference Finals is scheduled to start at 8:00PM ET.

• Who: Indiana Pacers vs. New York Knicks
• Date: Wednesday, May 21, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: Madison Square Garden
• NBA Playoffs Bracket: Updated NBA Playoffs bracket and schedule

The winner of the 2025 NBA Conference Finals will progress to the NBA Finals. Game 1 of the best-of-seven series between the Pacers and Knicks is at New York's Madison Square Garden. Dimers.com's full preview of Wednesday's Pacers vs. Knicks matchup includes our prediction, picks and the latest betting odds.

Before making any Indiana vs. New York picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

Conclusion

We predict the Knicks, with a 66% win probability, will likely beat the Pacers in Game 1 of the 2025 Conference Finals.

AI and automation have enhanced this article to quickly deliver accurate Pacers vs. Knicks insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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