Illinois State vs. Oklahoma prediction: Oklahoma favored to win in college football Week 1, 2025

Oklahoma and Illinois State will lock horns in college football action at Gaylord Family Oklahoma Memorial Stadium on Saturday, commencing at 6:00PM ET.

Based on the latest simulation results, Dimers' proven college football model projects Oklahoma as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Illinois State vs. Oklahoma predictions page.

Illinois State vs. Oklahoma prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the outcome of Illinois State vs. Oklahoma 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives Oklahoma a 98% chance of defeating Illinois State. Our predicted final score has Oklahoma winning 48-12.

According to our model, the bookmakers have got it right, and Illinois State and Oklahoma each have a 50% chance of covering the spread, while the 60.5-point over/under has a 52% chance of going over.

Illinois State vs. Oklahoma odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type	Illinois State	Oklahoma
Spread	+39.5 (-105)	-39.5 (-115)
Moneyline	+8000	-100000
Total	o60.5 (-108)	u60.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Illinois State vs. Oklahoma picks and best bets

Our model's biggest edge in today's Illinois State vs. Oklahoma matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Illinois State vs. Oklahoma game-day updates and essential details

Saturday's college football action between Oklahoma and Illinois State at Gaylord Family Oklahoma Memorial Stadium is scheduled to start at 6:00PM ET.

• Who: Illinois State vs. Oklahoma
• Date: Saturday, August 30, 2025
• Time: 6:00PM ET/3:00PM PT
• Venue: Gaylord Family Oklahoma Memorial Stadium

Dimers.com's comprehensive preview of Saturday's Illinois State vs. Oklahoma matchup includes our prediction, picks and the latest betting odds.

Before making any Illinois State vs. Oklahoma picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Oklahoma, with a 98% win probability, will likely beat Illinois State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Illinois State vs. Oklahoma insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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