Houston Texans vs. Los Angeles Rams early prediction: Expert picks for NFL Week 1, 2025

The Houston Texans and Los Angeles Rams will meet in Week 1 of the NFL season at SoFi Stadium on Sunday, September 7, 2025, starting at 4:25PM ET.

Initial simulations from Dimers' trusted NFL model favor the Rams as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Texans vs. Rams predictions page.

Houston vs. LA Rams early predictions

Leveraging trusted machine learning and analysis, we have simulated the Texans vs. Rams game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Texans 42%, Rams 58%
• Predicted final score: Texans 21-23 Rams
• Spread: Texans (+2.5) 50%, Rams (-2.5) 50%
• Total points (43.5): Over 54%, Under 46%

As of August 31, 2025, these Texans-Rams numbers and predictions reflect the latest data and insights available.

Texans vs. Rams Week 1 details

The NFL Week 1 action between the Rams and Texans at SoFi Stadium is scheduled for September 7, 2025.

• Who: Houston Texans vs. Los Angeles Rams
• Date: Sunday, September 7, 2025
• Time: 4:25PM ET/1:25PM PT
• Venue: SoFi Stadium

Texans vs. Rams opening odds

We've researched the best betting odds across America for this Week 1 game, which are listed here:

• Spread: Texans +2.5 (-104), Rams -2.5 (-112)
• Moneyline: Texans +120, Rams -140
• Total: Over/Under 43.5 (-115/-105)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Rams, with a 58% win probability, will likely beat the Texans in Week 1 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Texans vs. Rams matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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