Houston Texans vs. Jacksonville Jaguars early prediction: Expert picks for NFL Week 3, 2025

The Houston Texans and Jacksonville Jaguars will meet in Week 3 of the NFL season at EverBank Stadium on Sunday, September 21, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Texans as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Texans vs. Jaguars predictions page.

Houston vs. Jacksonville early predictions

Leveraging trusted machine learning and analysis, we have simulated the Texans vs. Jaguars game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Texans 59%, Jaguars 41%
• Predicted final score: Texans 23-21 Jaguars
• Spread: Texans (-1.5) 53%, Jaguars (+1.5) 47%
• Total points (46.5): Over 44%, Under 56%

As of September 14, 2025, these Texans-Jaguars calculations and predictions reflect the latest data and insights available.

Texans vs. Jaguars Week 3 details

The NFL Week 3 matchup between the Jaguars and Texans at EverBank Stadium is scheduled for September 21, 2025.

• Who: Houston Texans vs. Jacksonville Jaguars
• Date: Sunday, September 21, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: EverBank Stadium

Texans vs. Jaguars opening odds

We've researched the best betting odds across America for this Week 3 game, which are listed here:

• Spread: Texans -1.5 (-110), Jaguars +1.5 (-110)
• Moneyline: Texans -125, Jaguars +105
• Total: Over/Under 46.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Texans, with a 59% win probability, will likely beat the Jaguars in Week 3 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Texans vs. Jaguars matchup, with human oversight maintaining high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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