Astros vs. Blue Jays prediction: Why Toronto is favored to win Thursday's MLB matchup [9/11/2025]

The Toronto Blue Jays and Houston Astros will lock horns in MLB action at Rogers Centre on Thursday, starting at 3:07PM ET.

The Blue Jays will start Kevin Gausman (9-10, 3.63 ERA), while the Astros have opted for Cristian Javier (1-2, 4.43 ERA).

Based on updated simulation results, Dimers' advanced MLB model predicts the Blue Jays as the most likely winner of today's game.

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Astros vs. Blue Jays predictions page.

Blue Jays vs. Astros prediction: Who will win, cover the run line?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Thursday's MLB matchup between the Astros and Blue Jays 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Blue Jays a 57% chance of defeating the Astros.

According to our model, the Astros (+1.5) have a 60% chance of covering the run line, while the 8.5-run over/under has a 55% chance of going over.

Astros vs. Blue Jays odds [9/11/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	Blue Jays
Run Line	+1.5 (-154)	-1.5 (+130)
Moneyline	+140	-163
Total	o8.5 (-105)	u8.5 (-104)

All odds are correct at the time of publication and are subject to change.

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Astros vs. Blue Jays picks and best bets

Our model's strongest edge in today's Astros vs. Blue Jays matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Astros vs. Blue Jays game-day updates and essential details

Thursday's MLB game between the Blue Jays and Astros at Rogers Centre is scheduled to begin at 3:07PM ET.

• Who: Houston Astros vs. Toronto Blue Jays
• Date: Thursday, September 11, 2025
• Time: 3:07PM ET/12:07PM PT
• Venue: Rogers Centre

Dimers' in-depth preview of Thursday's Astros vs. Blue Jays matchup includes our prediction, picks and the latest betting odds.

Before making any Astros vs. Blue Jays picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Blue Jays, with a 57% win probability, will likely beat the Astros on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Blue Jays insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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