Astros vs. Rangers prediction: Why Houston is favored to win Friday's MLB matchup [9/5/2025]

The Texas Rangers will take on the Houston Astros, in what is expected to be a close MLB game, at Globe Life Field on Friday, commencing at 8:05PM ET.

The Rangers will start Merrill Kelly (11-7, 3.24 ERA), pitting him against Colton Gordon (4-4, 5.64 ERA) for the Astros.

Based on updated simulations, Dimers' advanced MLB model predicts the Astros as the most likely winner of today's game.

For further insights into Friday's matchup, including best bets and picks, visit our interactive Astros vs. Rangers predictions page.

Rangers vs. Astros prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the result of Friday's MLB matchup between the Astros and Rangers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Astros a 52% chance of defeating the Rangers.

According to our model, the Astros (+1.5) have a 67% chance of covering the run line, while the 8-run over/under has a 56% chance of going over.

Astros vs. Rangers odds [9/5/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	Rangers
Run Line	+1.5 (-194)	-1.5 (+170)
Moneyline	+106	-124
Total	o8 (-104)	u8 (-115)

All odds are correct at the time of publication and are subject to change.

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Astros vs. Rangers picks and best bets

Our model's biggest edge in today's Astros vs. Rangers matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

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Astros vs. Rangers game-day updates and essential details

Friday's MLB game between the Rangers and Astros at Globe Life Field is scheduled to commence at 8:05PM ET.

• Who: Houston Astros vs. Texas Rangers
• Date: Friday, September 5, 2025
• Time: 8:05PM ET/5:05PM PT
• Venue: Globe Life Field

Dimers.com's full preview of Friday's Astros vs. Rangers matchup includes our prediction, picks and the latest betting odds.

Before making any Astros vs. Rangers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Astros, with a 52% win probability, will likely beat the Rangers on Friday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Rangers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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