Astros vs. Rays Prediction: Close Contest Projected After New Data Released for Tuesday's MLB Matchup [5/20/2025]

The Tampa Bay Rays will square off with the Houston Astros in MLB action at George M. Steinbrenner Field on Tuesday, starting at 7:05PM ET.

Zack Littell (3-5, 4.31 ERA) will get the ball for the Rays, pitting him against Brandon Walter (0-0, 0.00 ERA) for the Astros.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts an equal chance for both the Rays and Astros to win today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Houston-Tampa Bay game," said Dimers' Chief Content Officer, Nick Slade.

"Based on the latest updates and extensive data, we predict a 50-50 chance for both the Rays and Astros, making it a highly competitive matchup."

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Astros vs. Rays predictions page.

Rays vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB game between the Astros and Rays 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently can't split the two teams, giving both the Astros and Rays a 50% chance of winning the game.

According to our model, the Astros (+1.5) have a 67% chance of covering the run line, while the 9-run over/under has a 53% chance of staying under.

Astros vs. Rays Odds [5/20/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	Rays
Run Line	+1.5 (-192)	-1.5 (+160)
Moneyline	+110	-125
Total	o9 (-120)	u9 (+100)

All odds are correct at the time of publication and are subject to change.

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Astros vs. Rays Picks and Best Bets

Our model's biggest edge in today's Astros vs. Rays matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Astros vs. Rays Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Rays and Astros at George M. Steinbrenner Field is scheduled to begin at 7:05PM ET.

• Who: Houston Astros vs. Tampa Bay Rays
• Date: Tuesday, May 20, 2025
• Time: 7:05PM ET/4:05PM PT
• Venue: George M. Steinbrenner Field

Dimers.com's in-depth preview of Tuesday's Astros vs. Rays matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. Tampa Bay picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict a close game between the Astros and Rays on Tuesday, with each team having a 50% chance of winning.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Rays insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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