Astros vs. Mariners Prediction: Seattle Predicted to Win Sunday's MLB Matchup [7/20/2025]

MLB action continues on Sunday at 4:10PM ET as the Houston Astros take on the Seattle Mariners at T-Mobile Park.

The Mariners will start Bryan Woo (8-4, 2.75 ERA), pitting him against Hunter Brown (9-4, 2.43 ERA) for the Astros.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Mariners as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Astros-Mariners game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Mariners with a win probability of 58%, while the Astros have 42%."

For further insights into Sunday's matchup, including best bets and picks, visit our interactive Astros vs. Mariners predictions page.

Mariners vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB game between the Astros and Mariners 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Mariners a 58% chance of defeating the Astros.

According to our model, the Astros (+1.5) have a 63% chance of covering the run line, while the 6.5-run over/under has a 52% chance of going over.

Astros vs. Mariners Odds [7/20/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	Mariners
Run Line	+1.5 (-188)	-1.5 (+180)
Moneyline	+124	-140
Total	o6.5 (+104)	u6.5 (-117)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Astros vs. Mariners Picks and Best Bets

Our model's strongest edge in today's Astros vs. Mariners matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Astros vs. Mariners Game-Day Updates and Essential Details

Sunday's MLB game between the Mariners and Astros at T-Mobile Park is scheduled to begin at 4:10PM ET.

• Who: Houston Astros vs. Seattle Mariners
• Date: Sunday, July 20, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: T-Mobile Park

Dimers.com's full preview of Sunday's Astros vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any Astros vs. Mariners picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Sports Betting Deals Available for Sunday

To make the most of Sunday's big day of sports, headlined by the final round of play at the Open Championship at Royal Portrush, check out details on the latest Bet365 bonus code "DIMERS" that secures the choice of two excellent signup promotions. Don't miss out!

Conclusion

We predict the Mariners, with a 58% win probability, will likely beat the Astros on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most accurate probabilities for the World Series, American League, National League and each division.