Astros vs. Mariners Prediction: Seattle Predicted to Win Saturday's MLB Matchup [7/19/2025]

The Seattle Mariners and Houston Astros will lock horns in MLB action at T-Mobile Park on Saturday, starting at 9:40PM ET.

The Mariners will start Logan Evans (3-3, 3.76 ERA), up against Lance McCullers (2-4, 6.48 ERA) for the Astros.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Mariners as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Astros vs. Mariners predictions page.

Mariners vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Saturday's MLB game between the Astros and Mariners 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Mariners a 54% chance of beating the Astros.

According to our model, the Astros (+1.5) have a 66% chance of covering the run line, while the 8-run over/under has an equal 50-50 chance of hitting.

Astros vs. Mariners Odds [7/19/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	Mariners
Run Line	+1.5 (-184)	-1.5 (+165)
Moneyline	+115	-131
Total	o8 (-110)	u8 (-108)

All odds are correct at the time of publication and are subject to change.

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Astros vs. Mariners Picks and Best Bets

Our model's biggest edge in today's Astros vs. Mariners matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Astros vs. Mariners Game-Day Updates and Essential Details

Saturday's MLB game between the Mariners and Astros at T-Mobile Park is scheduled to commence at 9:40PM ET.

• Who: Houston Astros vs. Seattle Mariners
• Date: Saturday, July 19, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: T-Mobile Park

Dimers.com's in-depth preview of Saturday's Astros vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any Astros vs. Mariners picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Mariners, with a 54% win probability, will likely beat the Astros on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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