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Astros vs. Brewers Prediction: Houston Predicted to Win Tuesday's MLB Matchup [5/6/2025]

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Written by Dave Garofolo

Our expert prediction for Tuesday's Houston Astros vs Milwaukee Brewers matchup.

Houston Astros-Milwaukee Brewers Predictions and Game Preview.
American Family Field sets the stage for the MLB matchup between the Houston Astros and Milwaukee Brewers this Tuesday.

The Milwaukee Brewers will face the Houston Astros in MLB action at American Family Field on Tuesday, starting at 7:40PM ET.

The Brewers will start Chad Patrick (1-3, 2.87 ERA), up against Hayden Wesneski (1-2, 3.86 ERA) for the Astros.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Houston-Milwaukee game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Astros with a win probability of 51%, compared to 49% for the Brewers."

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Astros vs. Brewers predictions page.

Brewers vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Tuesday's MLB game between the Astros and Brewers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Astros a 51% chance of beating the Brewers.

According to our model, the Astros (+1.5) have a 68% chance of covering the run line, while the over/under total of 8 runs has a 51% chance of going over.

 

Astros vs. Brewers Odds [5/6/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Astros Brewers
Run Line +1.5 (-194) -1.5 (+164)
Moneyline +110 -120
Total o8 (-108) u8 (-110)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Astros vs. Brewers Picks and Best Bets

Our model's strongest edge in today's Astros vs. Brewers matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Astros vs. Brewers Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Brewers and Astros at American Family Field is scheduled to commence at 7:40PM ET.

Dimers.com's full preview of Tuesday's Astros vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. Milwaukee picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Astros, with a 51% win probability, will likely beat the Brewers on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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