Astros vs. Marlins Prediction: Houston Predicted to Win Wednesday's MLB Matchup [8/6/2025]

The Miami Marlins and Houston Astros are scheduled to meet in MLB action at loanDepot park on Wednesday, starting at 4:40PM ET.

Janson Junk (5-2, 3.86 ERA) will start for the Marlins, up against Spencer Arrighetti (1-1, 5.59 ERA) for the Astros.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's Astros-Marlins game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Astros' chance of winning at 53%, with the Marlins at 47%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Astros vs. Marlins predictions page.

Marlins vs. Astros Prediction: Who Will Win?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's MLB game between the Astros and Marlins 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Astros a 53% chance of beating the Marlins.

According to our model, the 8-run over/under has a 51% chance of going over.

Astros vs. Marlins Odds [8/6/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	Marlins
Moneyline	-102	-115
Total	o8 (-118)	u8 (-103)

All odds are correct at the time of publication and are subject to change.

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Astros vs. Marlins Picks and Best Bets

Our model's strongest edge in today's Astros vs. Marlins matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Astros vs. Marlins Game-Day Updates and Essential Details

Wednesday's MLB game between the Marlins and Astros at loanDepot park is scheduled to begin at 4:40PM ET.

• Who: Houston Astros vs. Miami Marlins
• Date: Wednesday, August 6, 2025
• Time: 4:40PM ET/1:40PM PT
• Venue: loanDepot park

Dimers.com's comprehensive preview of Wednesday's Astros vs. Marlins matchup includes our prediction, picks and the latest betting odds.

Before making any Astros vs. Marlins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Astros, with a 53% win probability, will likely beat the Marlins on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Marlins insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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