Astros vs. White Sox Prediction: Houston Predicted to Win Saturday's MLB Matchup [5/3/2025]

The Chicago White Sox will square off with the favored Houston Astros in MLB action at Rate Field on Saturday, starting at 2:10PM ET.

The White Sox will start Davis Martin (1-3, 3.24 ERA), while the Astros are going with Hunter Brown (4-1, 1.22 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Houston-CHI White Sox game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Astros are more likely to win, while the White Sox have a lower chance of victory."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Astros vs. White Sox predictions page.

White Sox vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the result of Saturday's MLB game between the Astros and White Sox 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Astros a 67% chance of defeating the White Sox.

According to our model, the Astros (-1.5) have a 54% chance of covering the run line, while the 7.5-run over/under has a 55% chance of going over.

Astros vs. White Sox Odds [5/3/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	White Sox
Run Line	-1.5 (-128)	+1.5 (+114)
Moneyline	-225	+200
Total	o7.5 (-110)	u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Astros vs. White Sox Picks and Best Bets

Our model's strongest edge in today's Astros vs. White Sox matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Astros vs. White Sox Game-Day Updates and Essential Details

Saturday's MLB action between the White Sox and Astros at Rate Field is scheduled to start at 2:10PM ET.

• Who: Houston Astros vs. Chicago White Sox
• Date: Saturday, May 3, 2025
• Time: 2:10PM ET/11:10AM PT
• Venue: Rate Field

Dimers.com's comprehensive preview of Saturday's Astros vs. White Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. CHI White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Astros, with a 67% win probability, will likely beat the White Sox on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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