Astros vs. White Sox Prediction: Houston Predicted to Win Friday's MLB Matchup [5/2/2025]

The Chicago White Sox will square off with the favored Houston Astros in MLB action at Rate Field on Friday, starting at 7:40PM ET.

Jonathan Cannon (1-3, 4.50 ERA) will start for the White Sox, pitting him against Framber Valdez (1-3, 4.00 ERA) for the Astros.

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Houston-CHI White Sox game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Astros' chance of winning is 66%, while the White Sox' is 34%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Astros vs. White Sox predictions page.

White Sox vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Friday's MLB game between the Astros and White Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Astros a 66% chance of defeating the White Sox.

According to our model, the Astros (-1.5) have a 53% chance of covering the run line, while the 8-run over/under has a 54% chance of staying under.

Astros vs. White Sox Odds [5/2/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Astros	White Sox
Run Line	-1.5 (-130)	+1.5 (+114)
Moneyline	-220	+198
Total	o8 (-102)	u8 (-115)

All odds are correct at the time of publication and are subject to change.

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Astros vs. White Sox Picks and Best Bets

Our model's biggest edge in today's Astros vs. White Sox matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Astros vs. White Sox Game-Day Updates and Essential Details

Friday's MLB game between the White Sox and Astros at Rate Field is scheduled to begin at 7:40PM ET.

• Who: Houston Astros vs. Chicago White Sox
• Date: Friday, May 2, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Rate Field

Dimers.com's in-depth preview of Friday's Astros vs. White Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. CHI White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Astros, with a 66% win probability, will likely beat the White Sox on Friday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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