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Astros vs. Orioles prediction: Baltimore favored to win Saturday's MLB matchup [8/23/2025]

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Written by Jason Bevilacqua

Get Houston Astros vs Baltimore Orioles predictions for MLB Saturday.

Houston Astros-Baltimore Orioles Predictions and Game Preview.
Houston Astros vs. Baltimore Orioles MLB prediction for Saturday, August 23, 2025.

The Baltimore Orioles will take on the Houston Astros in MLB action at Oriole Park at Camden Yards on Saturday, starting at 7:05PM ET.

The Orioles will start Dean Kremer (9-9, 3.97 ERA), while the Astros will counter with Cristian Javier (1-1, 3.38 ERA).

Based on updated simulations, Dimers' advanced MLB model projects the Orioles as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Astros vs. Orioles predictions page.

Orioles vs. Astros prediction: Who will win, cover the run line?

Using innovative machine learning and data analysis, we have simulated the outcome of Saturday's MLB matchup between the Astros and Orioles 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Orioles a 51% chance of beating the Astros.

According to our model, the Astros (+1.5) have a 66% chance of covering the run line, while the over/under total of 9 runs has an equal 50-50 chance of hitting.

 

Astros vs. Orioles odds [8/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Astros Orioles
Run Line +1.5 (-200) -1.5 (+165)
Moneyline +100 -118
Total o9 (-105) u9 (-113)

All odds are correct at the time of publication and are subject to change.

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Astros vs. Orioles picks and best bets

Our model's strongest edge in today's Astros vs. Orioles matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Astros vs. Orioles game-day updates and essential details

Saturday's MLB action between the Orioles and Astros at Oriole Park at Camden Yards is scheduled to start at 7:05PM ET.

Dimers.com's comprehensive preview of Saturday's Astros vs. Orioles matchup includes our prediction, picks and the latest betting odds.

Before making any Astros vs. Orioles picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Orioles, with a 51% win probability, will likely beat the Astros on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest projections for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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