Hampton vs. Howard prediction: Hampton favored to win in college football Week 4, 2025

Howard will square off with Hampton in Week 4 college football action at Audi Field on Saturday, starting at 4:00PM ET.

Based on the latest simulations, Dimers' proven college football model projects Hampton as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Hampton vs. Howard predictions page.

Hampton vs. Howard prediction: Who will win, cover the spread?

Using innovative machine learning and data analysis, we have simulated the result of Hampton vs. Howard 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Hampton a 55% chance of beating Howard. Our predicted final score has Hampton winning 25-23.

According to our model, Howard (+3.5) has a 58% chance of covering the spread, while the 46.5-point over/under has a 59% chance of staying under.

Hampton vs. Howard odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Hampton	Howard
Spread	-3.5 (-110)	+3.5 (-110)
Moneyline	-160	+154
Total	o46.5 (-110)	u46.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Hampton vs. Howard picks and best bets

Our model's biggest edge in today's Hampton vs. Howard matchup is on the spread.

Our expert predictions, matched against the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Hampton vs. Howard game-day updates and essential details

Saturday's college football action between Howard and Hampton at Audi Field is scheduled to commence at 4:00PM ET.

• Who: Hampton vs. Howard
• Date: Saturday, September 20, 2025
• Time: 4:00PM ET/1:00PM PT
• Venue: Audi Field

Dimers' full preview of Saturday's Hampton vs. Howard matchup includes our prediction, picks and the latest betting odds.

Before making any Hampton vs. Howard picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Hampton, with a 55% win probability, will likely beat Howard on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Hampton vs. Howard insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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