Guadalajara vs. Toluca prediction, odds, Liga MX picks [9/20/2025]

Guadalajara will take on Toluca in Liga MX action on Saturday, beginning at 9:07PM ET.

Based on the latest simulation results, Dimers' advanced Liga MX model projects Toluca as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Guadalajara vs. Toluca predictions page.

Guadalajara vs. Toluca prediction: Who will win?

Using trusted machine learning and data analysis, we have simulated the result of Saturday's Liga MX game between Guadalajara and Toluca 10,000 times as part of our Liga MX predictions coverage.

Our leading predictive model currently indicates a 34.7% chance of Guadalajara winning, a 39.7% chance for Toluca, and a 25.6% chance of a draw.

Additionally, the 2.5-goal over/under has a 51% chance of going over, according to our model.

Guadalajara vs. Toluca odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Moneyline

Guadalajara	Toluca	Draw
+210	+135	+240

Total Goals

Over 2.5	Under 2.5
-140	+114

All odds are correct at the time of publication and are subject to change.

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Guadalajara vs. Toluca picks and best bets

Our model's biggest edge in today's Guadalajara vs. Toluca matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Guadalajara vs. Toluca: Correct score and BTTS predictions

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

Final Score	Probability
GUA 1-1 TOL	12.1%
GUA 0-1 TOL	9.3%
GUA 1-0 TOL	8.6%

When it comes to the both teams to score (BTTS) market, we project a 55.3% chance that both Guadalajara and Toluca score, and a 44.7% probability of at least one team being held goalless.

These predictions are based on each team's average score after 10,000 simulations, which means the most likely correct score may differ from our predicted winner.

Guadalajara vs. Toluca game-day updates and essential details

Saturday's matchup between Guadalajara and Toluca is scheduled to commence at 9:07PM ET.

• Who: Guadalajara vs. Toluca
• Date: Saturday, September 20, 2025
• Time: 9:07PM ET/6:07PM PT

Dimers' full preview of Saturday's Guadalajara vs. Toluca matchup includes our prediction, picks and the latest betting odds.

Before making any Toluca vs. Guadalajara picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

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Conclusion

According to our computer model, Guadalajara has a 34.7% win probability on Saturday, Toluca has a 39.7% win probability, and there is a 25.6% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Guadalajara vs. Toluca insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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