Guadalajara vs. Tigres UANL prediction, odds, Liga MX picks [9/17/2025]

Liga MX action continues on Wednesday at 9:07PM ET as Tigres UANL squares off with Guadalajara at .

Based on the latest simulation results, Dimers' proven Liga MX model predicts Guadalajara as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Guadalajara-Tigres UANL game 10,000 times," said Dave Garofolo from Dimers.

"Taking into account the most current updates and numerous additional factors, our prediction gives Guadalajara a 38.4% chance of winning, Tigres UANL a 34.9% chance, and a 26.7% chance of a draw."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Guadalajara vs. Tigres UANL predictions page.

Guadalajara vs. Tigres UANL prediction: Who will win?

Using trusted machine learning and data, we have simulated the result of Wednesday's Liga MX game between Guadalajara and Tigres UANL 10,000 times as part of our Liga MX predictions coverage.

Our independent predictive model currently suggests a 38.4% chance of Guadalajara winning, a 34.9% chance for Tigres UANL, and a 26.7% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 53% chance of staying under, according to our model.

Guadalajara vs. Tigres UANL odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Moneyline

Guadalajara	Tigres UANL	Draw
+140	+200	+220

Total Goals

Over 2.5	Under 2.5
-112	-108

All odds are correct at the time of publication and are subject to change.

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Guadalajara vs. Tigres UANL picks and best bets

Our model's biggest edge in today's Guadalajara vs. Tigres UANL matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Guadalajara vs. Tigres UANL: Correct score and BTTS predictions

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

Final Score	Probability
GUA 1-1 TUA	12.7%
GUA 1-0 TUA	10.3%
GUA 0-1 TUA	9.7%

When it comes to the both teams to score (BTTS) market, we project a 51.8% chance of the yes hitting, and a 48.2% probability of at least one team being held goalless.

These predictions are based on each team's average score after 10,000 simulations, which means the most likely correct score can differ from our predicted winner.

Guadalajara vs. Tigres UANL game-day updates and essential details

Wednesday's game between Guadalajara and Tigres UANL is scheduled to commence at 9:07PM ET.

• Who: Guadalajara vs. Tigres UANL
• Date: Wednesday, September 17, 2025
• Time: 9:07PM ET/6:07PM PT

Dimers' in-depth preview of Wednesday's Guadalajara vs. Tigres UANL matchup includes our prediction, picks and the latest betting odds.

Before making any Tigres UANL vs. Guadalajara picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Guadalajara has a 38.4% win probability on Wednesday, Tigres UANL has a 34.9% win probability, and there is a 26.7% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Guadalajara vs. Tigres UANL insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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