Guadalajara vs. San Luis Prediction, Odds, Liga MX Picks [7/26/2025]

Liga MX action continues on Saturday at 7:07PM ET as Atletico San Luis locks horns with Guadalajara at Estadio AKRON.

Based on updated simulation results, Dimers' proven Liga MX model (see Dimers Pro for full access) predicts Guadalajara as the most likely winner of today's game.

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Guadalajara vs. Atletico San Luis predictions page.

Guadalajara vs. Atletico San Luis Prediction: Who Will Win?

Using powerful machine learning and data, we have simulated the outcome of Saturday's Liga MX matchup between Guadalajara and Atletico San Luis 10,000 times as part of our Liga MX predictions coverage.

Our famous predictive model currently suggests a 60.8% chance of Guadalajara winning, a 17.3% chance for Atletico San Luis, and a 21.8% chance of a draw.

Additionally, the 2.5-goal over/under has a 53% chance of going over, according to our model.

Guadalajara vs. Atletico San Luis Odds

We have researched the best Liga MX odds in America for this game, which are listed here:

Moneyline

Guadalajara	Atletico San Luis	Draw
-200	+650	+340

Total Goals

Over 2.5	Under 2.5
-130	+106

All odds are correct at the time of publication and are subject to change.

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Guadalajara vs. Atletico San Luis Picks and Best Bets

Our model's strongest edge in today's Guadalajara vs. Atletico San Luis matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Guadalajara vs. Atletico San Luis: Correct Score and BTTS Predictions

Here are the top three most likely final scores according to our model, with a 1-0 Guadalajara win being the most probable:

Final Score	Probability
GUA 1-0 ASL	11.4%
GUA 2-0 ASL	10.9%
GUA 1-1 ASL	10.4%

When it comes to the both teams to score (BTTS) market, we project a 50.8% chance that both teams scoring, and a 49.2% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations.

Guadalajara vs. San Luis Game-Day Updates and Essential Details

Saturday's matchup between Guadalajara and Atletico San Luis at Estadio AKRON is scheduled to begin at 7:07PM ET.

• Who: Guadalajara vs. Atletico San Luis
• Date: Saturday, July 26, 2025
• Time: 7:07PM ET/4:07PM PT
• Venue: Estadio AKRON

Dimers.com's comprehensive preview of Saturday's Guadalajara vs. Atletico San Luis matchup includes our prediction, picks and the latest betting odds.

Before making any San Luis vs. Guadalajara picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Guadalajara has a 60.8% win probability on Saturday, Atletico San Luis has a 17.3% win probability, and there is a 21.8% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Guadalajara vs. Atletico San Luis insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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