Green Bay Packers vs. Dallas Cowboys early prediction: Expert picks for NFL Week 4, 2025

The Green Bay Packers and Dallas Cowboys will meet in Week 4 of the NFL season at AT&T Stadium on Sunday, September 28, 2025, starting at 8:20PM ET.

Initial simulations from Dimers' trusted NFL model favor the Packers as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Packers vs. Cowboys predictions page.

Green Bay vs. Dallas early predictions

Leveraging trusted machine learning and analysis, we have simulated the Packers vs. Cowboys game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Packers 60%, Cowboys 40%
• Predicted final score: Packers 24-21 Cowboys
• Spread: Packers (-1.5) 53%, Cowboys (+1.5) 47%
• Total points (47.5): Over 46%, Under 54%

As of September 21, 2025, these Packers-Cowboys numbers and predictions reflect the latest data and insights available.

Packers vs. Cowboys Week 4 details

The NFL Week 4 action between the Cowboys and Packers at AT&T Stadium is scheduled for September 28, 2025.

• Who: Green Bay Packers vs. Dallas Cowboys
• Date: Sunday, September 28, 2025
• Time: 8:20PM ET/5:20PM PT
• Venue: AT&T Stadium

Packers vs. Cowboys opening odds

We've researched the best betting odds across America for this Week 4 game, which are listed here:

• Spread: Packers -1.5 (-112), Cowboys +1.5 (-108)
• Moneyline: Packers -125, Cowboys +105
• Total: Over/Under 47.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Packers, with a 60% win probability, will likely beat the Cowboys in Week 4 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Packers vs. Cowboys matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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