Gonzaga vs. Santa Clara Prediction: Gonzaga Predicted to Win College Basketball Matchup [2/25/2025]

College basketball action continues on Tuesday at 11:00PM ET as the favored Gonzaga squares off with Santa Clara in college basketball action at Leavey Center.

Based on updated simulations, Dimers' advanced college basketball model (see Dimers Pro for full access) predicts Gonzaga as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Gonzaga-Santa Clara game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows Gonzaga with a win probability of 64%, compared to 36% for Santa Clara."

For a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Gonzaga vs. Santa Clara predictions page.

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Gonzaga vs. Santa Clara Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Tuesday's NCAA basketball matchup between Gonzaga and Santa Clara 10,000 times as part of our college basketball predictions coverage.

Our leading predictive model gives Gonzaga a 64% chance of beating Santa Clara. Our predicted final score has Gonzaga winning 80-76.

According to our model, Santa Clara (+6.5) has a 61% chance of covering the spread, while the over/under total of 163.5 points has a 55% chance of staying under.

Gonzaga vs. Santa Clara Odds

We have researched the best College Basketball odds in America for this game, which are listed here:

Bet Type	Gonzaga	Santa Clara
Spread	-6.5 (-110)	+6.5 (-105)
Moneyline	-275	+240
Total	o163.5 (-110)	u163.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Gonzaga vs. Santa Clara Picks and Best Bets

Our model's strongest edge in today's Gonzaga vs. Santa Clara matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Gonzaga vs. Santa Clara Game-Day Updates and Essential Details

Tuesday's college basketball action between Santa Clara and Gonzaga at Leavey Center is scheduled to commence at 11:00PM ET.

• Who: Gonzaga vs. Santa Clara
• Date: Tuesday, February 25, 2025
• Time: 11:00PM ET/8:00PM PT
• Venue: Leavey Center

Dimers.com's full preview of Tuesday's Gonzaga vs. Santa Clara matchup includes our prediction, picks and the latest betting odds.

Before making any Gonzaga vs. Santa Clara picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Conclusion

We predict Gonzaga, with a 64% win probability, will likely beat Santa Clara on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Gonzaga vs. Santa Clara insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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