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Giants vs. Cardinals Week 2 Prediction and Odds - September 17, 2023

NFL Week 2 action continues on Sunday at 4:05PM ET as the New York Giants take on the Arizona Cardinals at State Farm Stadium.
Dimers' best betting picks for Giants vs. Cardinals, as well as our score prediction, betting odds and touchdown scorer probabilities, are detailed in this article.
Today's NY Giants vs. Arizona betting analysis is presented by Bet365, which has a Bet $1, Get $365 in Bonus Bets offer for new customers.
Who Will Win: Giants vs. Cardinals
Using advanced computer power and data, Dimers.com has simulated Sunday's Giants-Cardinals NFL matchup 10,000 times.
Dimers' popular predictive analytics model, DimersBOT, currently gives the Giants a 71% chance of winning against the Cardinals in Week 2 of the NFL season.
More: Giants vs. Cardinals Simulated 10K Times
Giants vs. Cardinals Odds
- Spread: Cardinals +4.5 (-110), Giants -4.5 (-110)
- Moneyline: Cardinals +182, Giants -225
- Total: Over/Under 36.5 (-112/-110)
The Cardinals are +4.5 underdogs versus the Giants, with -110 at BetMGM the best odds currently available.
For the favored Giants (-4.5) to cover the spread, BetMGM also has the best odds currently on offer at -110.
FanDuel Sportsbook currently has the best moneyline odds for the Cardinals at +182. That means you can bet $100 to profit $182, earning a total payout of $282, if they win.
On the other hand, PointsBet currently has the best moneyline odds for the Giants at -225, where you can risk $225 to win $100, for a total payout of $325, if they come out on top.
The Over/Under for total points scored is set at 36.5 with PointsBet, which currently has the best odds for the Over at -112, while DraftKings Sportsbook currently has the best odds for the Under at -110.
As always, make sure you check the sportsbooks you can bet with in your state for the best NFL odds and lines.
According to DimersBOT, the Giants (-4.5) have a 54% chance of covering the spread, while the 36.5-point Over/Under has a 57% chance of going Over.
More: Live Win Probabilities for All Major Sports
Best Bets: Giants vs. Cardinals
- Spread: Giants -4.5 @ -110 via BetMGM (54% probability)
- Moneyline: Giants @ -225 via PointsBet (71% probability)
- Total: Over 36.5 @ -112 via PointsBet (57% probability)
Our best bets are based on complex simulations and betting expertise to help you make more informed investments with your state's legal sportsbooks.
Giants vs. Cardinals Prediction
Dimers.com's predicted final score for NY Giants vs. Arizona at State Farm Stadium in Week 2 has the Giants winning 22-17.
Click or tap on See Matchup to find out more.
Dimers has full betting coverage of this week's Giants-Cardinals game in Week 2, including pregame predictions, free picks, and live scores.
Giants vs. Cardinals Player Props
Who will score an anytime touchdown in Giants vs. Cardinals? The data is in.
Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Giants and Cardinals, as well as player stat projections.
And you know what, we provide this information to you for FREE to help you select the best prop bets for Sunday's game.
According to DimersBOT, New York's Saquon Barkley is most likely to score the first touchdown in Giants vs. Cardinals.
DimersBOT gives Barkley a 13.9% chance of scoring the first TD at State Farm Stadium, while the Giants RB is a 48.7% chance of scoring an anytime touchdown.
Scroll down for the full list of first and anytime TD scorer probabilities, which provide a great avenue for you to use this DraftKings Sportsbook offer, which unlocks $200 in bonus bets from a $5 bet on any of the below players.
First Touchdown Scorer Probabilities
New York Giants
- Saquon Barkley: 13.9% probability
- Daniel Jones: 9.2% probability
- Darren Waller: 7.3% probability
- Darius Slayton: 5.0% probability
- Parris Campbell: 4.7% probability
Arizona Cardinals
- James Conner: 12.3% probability
- Marquise Brown: 6.6% probability
- Rondale Moore: 5.2% probability
- Zach Ertz: 4.1% probability
- Trey McBride: 3.9% probability
Anytime Touchdown Scorer Probabilities
New York Giants
- Saquon Barkley: 48.7% probability
- Daniel Jones: 35.0% probability
- Darren Waller: 28.6% probability
- Darius Slayton: 20.7% probability
- Parris Campbell: 18.8% probability
Arizona Cardinals
- James Conner: 45.0% probability
- Marquise Brown: 26.7% probability
- Rondale Moore: 21.2% probability
- Zach Ertz: 18.2% probability
- Trey McBride: 16.5% probability
Giants-Cardinals Projected Player Stats
Of the starting quarterbacks, the Giants' Daniel Jones is projected for 216 passing yards, while the Cardinals' Joshua Dobbs is expected to throw for just 178 yards.
Giants Starting QB
- Daniel Jones: 216 projected yards
Cardinals Starting QB
- Joshua Dobbs: 178 projected yards
Giants Rushing
- Saquon Barkley: 72 projected yards
- Daniel Jones: 34 projected yards
- Matt Breida: 14 projected yards
Cardinals Rushing
- James Conner: 72 projected yards
- Keaontay Ingram: 13 projected yards
- Joshua Dobbs: 9 projected yards
Giants Receiving
- Darren Waller: 48 projected yards
- Darius Slayton: 40 projected yards
- Parris Campbell: 35 projected yards
- Isaiah Hodgins: 30 projected yards
- Jalin Hyatt: 21 projected yards
Cardinals Receiving
- Marquise Brown: 41 projected yards
- Rondale Moore: 36 projected yards
- Zach Ertz: 29 projected yards
- Michael Wilson: 25 projected yards
- Trey McBride: 24 projected yards
Remember, DimersBOT updates regularly, so check this article for any changes to our betting insights ahead of Giants vs. Cardinals on Sunday September 17, 2023.
Giants vs. Cardinals 2023
The NFL Week 2 matchup between the Cardinals and Giants at State Farm Stadium is scheduled to start at 4:05PM ET.
- Who: New York Giants vs. Arizona Cardinals
- Date: Sunday September 17, 2023
- Time: 4:05PM ET / 1:05PM PT
- Venue: State Farm Stadium
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Make Informed Sports Betting Decisions with Dimers
Dimers' picks are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.
While these Giants vs. Cardinals predictions can help you make informed decisions, it's vital that you gamble responsibly and manage your bankroll effectively.
For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
What Other NFL Games Are on Today?
The Giants and Cardinals aren't the only two NFL teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single NFL matchup via our NFL predictions. Not only do we provide with you quality predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out today!
In addition to our leading NFL predictions, Dimers also offers the best NFL prop bets today, projecting passing yards, touchdowns, and more against the best odds available every day of the NFL season.