Francisco Comesana vs. Andrey Rublev Prediction, Odds, Picks for ATP Cincinnati Open 2025

Francisco Comesana will square off with Andrey Rublev in the round of 16 at the ATP Cincinnati event on Wednesday.

Based on the latest simulation results, Dimers' proven tennis model (see Dimers Pro for full access) predicts Andrey Rublev as the most likely winner of the match. "We have simulated the outcome of Wednesday's Comesana-Rublev match 10,000 times," said Dimers data analyst Greg Butyn.

"With the latest updates and numerous other variables, we estimate Andrey Rublev's chance of winning at 73%, with Francisco Comesana at 27%."

For further insights into Wednesday's match, including best bets and picks, visit our interactive Comesana vs. Rublev predictions page.

Comesana vs. Rublev Prediction: Who Will Win and Advance to the Quarterfinals?

Using innovative machine learning and statistical analysis, we have simulated the result of Wednesday's Comesana-Rublev men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model gives Rublev a 73% chance of defeating Comesana at the ATP Cincinnati Open tournament.

Additionally, Rublev has a 69% chance of winning the first set, according to our model.

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Francisco Comesana vs. Andrey Rublev Odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Comesana	Rublev
Moneyline	+350	-500
First Set	+250	-333

All odds are correct at the time of publication and are subject to change.

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Comesana vs. Rublev Picks and Best Bets

Our model's strongest edge in today's Comesana vs. Rublev match is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Comesana vs. Rublev Updates and Essential Details

The ATP Cincinnati Open match between Francisco Comesana and Andrey Rublev is scheduled to start on Wednesday at 8:10PM ET.

• Who: Francisco Comesana vs. Andrey Rublev
• Date: Wednesday, August 13, 2025
• Approx. Time: 8:10PM ET/5:10PM PT
• Tournament: ATP Cincinnati, USA Men's Singles 2025
• Round: Round of 16

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Wednesday's Comesana vs. Rublev match includes our prediction, picks and the latest betting odds.

Before making any Francisco Comesana vs. Andrey Rublev picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Andrey Rublev, with a 73% win probability, will likely beat Francisco Comesana at the ATP Cincinnati Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Comesana vs. Rublev insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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