Frances Tiafoe vs. Jan-Lennard Struff prediction, odds, picks for US Open 2025

Frances Tiafoe and Jan-Lennard Struff are scheduled to meet in the third round of the US Open 2025 on Friday.

Based on the latest simulations, Dimers' proven tennis model predicts Frances Tiafoe as the most likely winner of the match.

For a closer look at Friday's match, including best bets and picks, visit our interactive Tiafoe vs. Struff predictions page.

Tiafoe vs. Struff prediction: Who will win and advance to the Round of 16?

Using powerful machine learning and data, we have simulated the outcome of Friday's Tiafoe-Struff men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Tiafoe a 76% chance of beating Struff in the US Open 2025.

Additionally, Tiafoe has a 70% chance of winning the first set, while the under 39.5 games has a 58% chance of hitting, according to our model.

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Frances Tiafoe vs. Jan-Lennard Struff odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Tiafoe	Struff
Moneyline	-275	+225
First Set	-189	+150
Total Games	o39.5 (-115)	u39.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Tiafoe vs. Struff picks and best bets

Our model's strongest edge in today's Tiafoe vs. Struff match is on the first set.

Our expert predictions, aligned with the current odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Tiafoe vs. Struff updates and essential details

The US Open 2025 match between Frances Tiafoe and Jan-Lennard Struff is scheduled to commence on Friday at 3:10PM ET.

• Who: Frances Tiafoe vs. Jan-Lennard Struff
• Date: Friday, August 29, 2025
• Approx. Time: 3:10PM ET/12:10PM PT
• Tournament: US Open Men's Singles 2025
• Round: Third round

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Friday's Tiafoe vs. Struff match includes our prediction, picks and the latest betting odds.

Before making any Frances Tiafoe vs. Jan-Lennard Struff picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

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Conclusion

We predict Frances Tiafoe, with a 76% win probability, will likely beat Jan-Lennard Struff at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Tiafoe vs. Struff insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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