Florida State vs. Virginia prediction: Florida State favored to win in college football Week 5, 2025

Virginia will square off with the favored Florida State in Week 5 college football action at Scott Stadium on Friday, with kickoff at 7:00PM ET.

Based on updated simulations, Dimers' proven college football model projects Florida State as the most likely winner of today's game.

For expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Florida State vs. Virginia predictions page.

Florida State vs. Virginia prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of Florida State vs. Virginia 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Florida State a 66% chance of defeating Virginia. Our predicted final score has Florida State winning 33-26.

According to our model, Virginia (+7.5) has a 55% chance of covering the spread, while the over/under total of 57.5 points has a 55% chance of going over.

Florida State vs. Virginia odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Florida State	Virginia
Spread	-7.5 (-120)	+7.5 (-110)
Moneyline	-265	+240
Total	o57.5 (+100)	u57.5 (-115)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Florida State vs. Virginia picks and best bets

Our model's strongest edge in today's Florida State vs. Virginia matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Florida State vs. Virginia game-day updates and essential details

Friday's college football action between Virginia and Florida State at Scott Stadium is scheduled to begin at 7:00PM ET.

• Who: Florida State vs. Virginia
• Date: Friday, September 26, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Scott Stadium

Dimers' in-depth preview of Friday's Florida State vs. Virginia matchup includes our prediction, picks and the latest betting odds.

Before making any Florida State vs. Virginia picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Conclusion

We predict Florida State, with a 66% win probability, will likely beat Virginia on Friday.

AI and automation have enhanced this article to quickly deliver accurate Florida State vs. Virginia insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Keep up with the latest college football news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the latest projections for the national title game and major conferences.