Florida State vs. Louisville Prediction: Louisville Predicted to Win College Basketball Matchup [2/22/2025]

Louisville and Florida State will meet in college basketball action at KFC Yum! Center on Saturday, with tipoff at 12:00PM ET.

Based on updated simulation results, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Louisville as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Our team has used the latest data to run 10,000 simulations of Saturday's Florida State-Louisville game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that Louisville is more likely to win, while Florida State has a lower chance of victory."

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Florida State vs. Louisville predictions page.

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Florida State vs. Louisville Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Florida State and Louisville 10,000 times as part of our college basketball predictions coverage.

Our independent predictive model currently gives Louisville a 90% chance of defeating Florida State. Our predicted final score has Louisville winning 84-69.

According to our model, Louisville (-13.5) has a 55% chance of covering the spread, while the over/under total of 154.5 points has an equal 50-50 chance of hitting.

Florida State vs. Louisville Odds

We have sourced the best College Basketball odds in America for this game, which are listed here:

Bet Type	Florida State	Louisville
Spread	+13.5 (-110)	-13.5 (-105)
Moneyline	+700	-1050
Total	o154.5 (-115)	u154.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Florida State vs. Louisville Picks and Best Bets

Our model's biggest edge in today's Florida State vs. Louisville matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Florida State vs. Louisville Game-Day Updates and Essential Details

Saturday's college basketball action between Louisville and Florida State at KFC Yum! Center is scheduled to start at 12:00PM ET.

• Who: Florida State vs. Louisville
• Date: Saturday, February 22, 2025
• Time: 12:00PM ET/9:00AM PT
• Venue: KFC Yum! Center

Dimers.com's in-depth preview of Saturday's Florida State vs. Louisville matchup includes our prediction, picks and the latest betting odds.

Before making any Florida State vs. Louisville picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

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Conclusion

We predict Louisville, with a 90% win probability, will likely beat Florida State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Florida State vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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