Elon University vs. Duke prediction: Duke favored to win in college football Week 1, 2025

Duke and Elon University will clash in college football action at Brooks Field at Wallace Wade Stadium on Thursday, beginning at 7:30PM ET.

Based on updated simulations, Dimers' proven college football model predicts Duke as the most likely winner of today's game.

For further insights into Thursday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Elon University vs. Duke predictions page.

Elon University vs. Duke prediction: Who will win, cover the spread?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Elon University vs. Duke 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Duke a 99% chance of defeating Elon University. Our predicted final score has Duke winning 43-7.

According to our model, the bookies have got it right, and Elon University and Duke each have a 50% chance of covering the spread, while the over/under total of 51.5 points has a 53% chance of staying under.

Elon University vs. Duke odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type	Elon University	Duke
Spread	+36.5 (-105)	-36.5 (-110)
Moneyline	+8000	-100000
Total	o51.5 (-108)	u51.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Elon University vs. Duke picks and best bets

Our model's strongest edge in today's Elon University vs. Duke matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Elon University vs. Duke game-day updates and essential details

Thursday's college football matchup between Duke and Elon University at Brooks Field at Wallace Wade Stadium is scheduled to commence at 7:30PM ET.

• Who: Elon University vs. Duke
• Date: Thursday, August 28, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Brooks Field at Wallace Wade Stadium

Dimers.com's full preview of Thursday's Elon University vs. Duke matchup includes our prediction, picks and the latest betting odds.

Before making any Elon University vs. Duke picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Duke, with a 99% win probability, will likely beat Elon University on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Elon University vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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